Captopril API

Captopril API About

Captopril(rINN)is anangiotensin-converting enzyme (ACE) inhibitorused for the treatment ofhypertensionand some types ofcongestive heart failure. Captopril was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process.

Specification:

Product name	Captopril
Appearance	White or almost white crystalline powder
Solubility	Freely soluble in water,in methylene chloride and in methanol. It dissolves in dilute solutions of alkali hydroxides.
Identification	Ir spectrum conformod tothat of captopril crs
Appearance of solutions	Clear and colorless
Melting range	Between 104 and 110
Specific optical rotation	-125 to -130
Related substance Ampa Captopril disulfide Single unknown impurity Tctal unknown impurities	Not more than 0.2% Not more than 1.0% Not more than 0.2% Not more than 0.5%
Heavy metals	Not more than 0.003%
Loss on drying	Not more than 1.0%
Sulphated ash	Not more than 0.2%
Assay	97.5%102.0% calculated on anhydrous basis

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

Key Properties and Applications

Captopril API distinguishes itself with excellent solubility and stable physical attributes. Due to its dependable antihypertensive action, it is extensively used in the formulation of medications aimed at controlling blood pressure. Pharmaceutical entities trust Captopril's purity and performance for consistent manufacturing outcomes.


Safe Storage and Longevity

Proper storage is essential to maintain the potency and quality of Captopril API. The compound should be kept away from moisture and stored in cool, dry conditions to ensure its five-year shelf life. Adhering to these storage guidelines helps prevent degradation and maintains the product's effectiveness.


Advantages in Pharmaceutical Manufacturing

Choosing Captopril API offers several benefits, including straightforward integration into a range of formulations. Its reliable chemical stability and antimicrobial capabilities make it a preferred choice among manufacturers, suppliers, and distributors, contributing to high-quality pharmaceutical products.