Buclizine API

Name: Buclizine API
Brand: WHITE SWAN PHARMACEUTICAL
Price: 23.0 USD
Availability: InStock

Price 23.0 USD ($)/ Kilograms

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MOQ : 10 Kilograms

Buclizine API Specification

Molecular Formula
C28H33ClN2

Storage
Room Temperature

Heavy Metal (%)
Not more than 10 ppm

Shelf Life
5 Years

Melting Point
105-110

Solubility
2.46e-04 g/L

Loss on Drying
Not more than 0.50% w/w

Boiling point
218

Medicine Name
Buclizine Hcl

Chemical Name
1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]piperazine

CAS No
129-74-8

Usage
Antiemetic

Appearance
White Crystalline Powder

Physical Form
Powder

Buclizine API Trade Information

Minimum Order Quantity
10 Kilograms

FOB Port
ALL INDIA

Payment Terms
Cash Advance (CA), Western Union, Paypal, Telegraphic Transfer (T/T), Cash in Advance (CID)

Delivery Time
2-3 Week

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)
Australia, North America, South America, Eastern Europe, Western Europe, Middle East, Africa, Asia, Central America

Main Domestic Market
All India

Certifications
WHO,GMP,COA,MSDS As Per Client Requirement

About Buclizine API

Buclizine is an antihistamine and anticholinergic of the piperazine derivative family. It is considered to be an antiemetic, similar to meclizine.

Properties	STANDARD
Condition of water solution	Passes test
Cd<%	0.0001
Lead(Pb)%max	0.001
Arsenic(As)%max	0.0001
Hg<%	0.0001
PH	3.2-3.8
Loss on drying %max	0.5
Specific Rotation	+17.5 - +18.5
Melting Point	110-120
E. Coli	Negative
Salmonelia	Negative
Coliforms	Negative
Yeast &Mould	<100g
Total plate count	<3000g
Appearance	White crystalline powder

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

Composition and Physical Properties

Buclizine Hcl is offered as a white crystalline powder characterized by a melting point range of 105-110C and a boiling point of 218C. The substance exhibits low solubility (2.46e-04 g/L) and complies with strict standards for heavy metals and moisture content. These properties underscore its suitability for pharmaceutical applications.

Proper Handling and Storage

To guarantee maximum shelf life and stability, Buclizine Hcl should be stored at room temperature in a tightly sealed container, away from moisture. Adhering to proper handling guidelines ensures the substance remains within specified limits for loss on drying and heavy metal content throughout its 5-year shelf life.

Therapeutic Use and Application

As an antiemetic, Buclizine Hcl is utilized in pharmaceutical formulations to prevent and manage nausea and vomiting. Its efficacy and established safety profile make it a preferred choice among healthcare providers and pharmaceutical manufacturers alike.

FAQ's of Buclizine API:

Q: How is Buclizine Hcl typically used in pharmaceuticals?

A: Buclizine Hcl is primarily used as an active ingredient in antiemetic pharmaceutical formulations to prevent and relieve nausea and vomiting.

Q: What is the recommended storage condition for Buclizine Hcl powder?

A: Buclizine Hcl should be stored at room temperature in a tightly closed container, away from direct moisture and light, to preserve its stability and efficacy.

Q: When does Buclizine Hcl expire, and what is its typical shelf life?

A: Buclizine Hcl offers a shelf life of up to 5 years when stored appropriately at room temperature, ensuring its potency and quality over time.

Q: Where can Buclizine Hcl be sourced from in India?

A: Buclizine Hcl can be procured from reliable distributors, exporters, manufacturers, suppliers, traders, and wholesalers across India, ensuring broad availability for pharmaceutical needs.

Q: What is the manufacturing process for Buclizine Hcl?

A: Buclizine Hcl is synthesized chemically and refined into a white crystalline powder, adhering to strict controls for purity, melting point, and heavy metal content, as mandated for pharmaceutical grade APIs.

Q: What are the main benefits of using Buclizine Hcl as an antiemetic?

A: Buclizine Hcl effectively controls symptoms of nausea and vomiting, contributing to patient comfort and improved treatment outcomes, particularly in clinical and hospital settings.

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