Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP) specific phosphodiesterases type 5 (PDE5). The physiologic mechanism of erection of the penis involves release of Nitric Oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzymes gyanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of Nitric Oxide (NO) by inhibiting phosphodiesterases type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Sildenafil causes increase level of cGMP in the corpus cavernosum resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.

Price:
Price 14.0 USD ($) / Box
Minimum Order Quantity : 1000 Boxes
Physical Form : Tablets
Ingredients : Shilajit+Amlarasayan
Dosage : As Directed By Physician
Storage Instructions : Store In A Cool & Dry Place
Price 5.0 USD ($) / Unit
Minimum Order Quantity : 1000 Units
Physical Form : Tablets
Ingredients : sildenafil citrate and dapoxetine
Price 13.5 USD ($) / Box
Minimum Order Quantity : 1000 Boxes
Physical Form : Tablets
Ingredients : Ivermectin 3/6/12 mg
Dosage : As Directed By Physician
Storage Instructions : Store In a Cool & Dry Place
Price 21 USD ($)
Minimum Order Quantity : As required by client.Box Box
Physical Form : Tablets
Ingredients : Empagliflozin
Dosage : As Directed By Physician
Storage Instructions : Store in Cool & Dry Place