Agomelatine API

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Agomelatine API Specification

Storage
Keep away from moisture

Molecular Formula
C15H17NO2

Shelf Life
5 Years

Molecular Weight
243.3 g/mol Grams (g)

Medicine Name
Agomelatine

Chemical Name
N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

CAS No
138112-76-2

Type
Other

Grade
Medicine Grade

Usage
Antiglaucoma

Appearance
White or white alike crystal powder

Physical Form
Powder

Agomelatine API Trade Information

FOB Port
ALL INDIA

Payment Terms
Cash Advance (CA), Western Union, Paypal, Telegraphic Transfer (T/T), Cash in Advance (CID)

Delivery Time
2-3 Week

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)
Middle East, Western Europe, Africa, Eastern Europe, Australia, South America, Asia, Central America, North America

Main Domestic Market
All India

Certifications
WHO,GMP,COA As Per Client Requirement

About Agomelatine API

Agomelatine is an extremely potent agonist at both melatonin receptors (MT1 and MT2), with additional antagonism at 5HT2C. It is a novel antidepressant with many desired in vivo properties, including neuroprotection and neurogenesis in depression-sensitive brain areas.

Agomelatine's efficacy appears to be due to both melatonergic and serotonergic properties. In neurogenesis assays, both in vitro and in vivo, the compound effects were differentially affected by antagonists for MT1/MT2 and 5HT2C, demonstrating actions through all three receptors.

Formula -C15H17NO2
Molar mass -243.301 g/mol
Bioavailability -1%
Protein binding -95%
Metabolism -hepatic (90% CYP1A2 and 10%CYP2C9)
Biological half-life- 1-2 hours Excretion -Renal (80%, mostly as metabolites)

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

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