Take gefitinib by mouth with or without food as directed by your doctor, usually once daily.
If you have trouble swallowing the tablet, you may place the tablet in a glass of water (4 to 8 ounces/120 to 240 milliliters). Stir well for 15 minutes. Drink all of the mixture right away. Rinse the cup with another 4 to 8 ounces (120 to 240 milliliters) of water and drink the rinse water to make sure you get the full dose.
Medications which reduce or block stomach acid (such as proton pump inhibitors/PPIs, H2 blockers, antacids) may reduce the absorption of gefitinib, making it work less well. If you take PPIs (such as omeprazole, lansoprazole), take gefitinib at least 12 hours before or 12 after the PPI. If you take antacids or H2 blockers (such as famotidine, ranitidine), take them at least 6 hours before or at least 6 hours after this medication.