What is Fosaprepitant?
Fosaprepitant is used with medications which cause nausea, vomiting caused by chemotherapy drug it works by inhibiting center which causes vomiting.
Fosaprepitant Injection Uses
This medication is used in the treatment of cancer
- Prevention of acute and delayed nausea associated with initial and repeated courses of highly emetogenic cancer
- Prevention of nausea, vomiting associated with moderately emetogenic cancer chemotherpy (MEC).
How Does Fosaprepitant Injection Work?
It is a prodrug of aprepitant which gives an antiemetic effect and has selective high-affinity antagonist of human substance P/neurokinin 1 receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CINV).
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