Doxylamine Succinate

Doxylamine Succinate

Product Details:

X

Product Description

Doxylamine is a first-generation antihistamine. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

Specification:

Test Items Specifications Results
Appearance White or almost white crystalline powder Conform
Solubility Very soluble in water, freelysoluble in alcohol Conform
 

 

 

Identification

1)    Melting range:103-108

2)    Ultraviolet absorption: UVmax=262.0nm

3)    Organic Nitrogenous Bases

4)    Succinic acid melting range:184-188

 

105

262.0 nm

 

Conform

 

186-188

Loss on drying <0.5% 0.3%
Residue on ignition <0.1% 0.1%
Related substances(GC) Total impurities<2.0%

Single impurity<1.0%

1.9%

1.0%

Residual solvents Diethyl ether<0.5%

Acetone<0.5%

Iso-propyl ether<0.5%


0.4%

0.4%

0.4%


Assay 98.0%-101.0%

(Calculated on anhydrous substance)

99.2%

 

Packaging details:

 

Packaging details: 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life: 5 years if sealed and store away from direct sun light.

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