Disulfiram API

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Disulfiram API Specification

Solubility
Practically insoluble in water; soluble in acetone, chloroform, ether, and benzene

Melting Point
69-72 Deg Celsius

Storage
Room Temperature

Medicine Name
Disulfiram

Chemical Name
Tetraethylthiuram disulfide

CAS No
97-77-8

Type
Pharmaceutical Intermediates

Usage
Alcoholic deterrent

Purity(%)
99%

Appearance
white with yellowness greenish hue,to light

Physical Form
Powder

Disulfiram API Trade Information

FOB Port
MUMBAI

Payment Terms
Telegraphic Transfer (T/T), Paypal, Western Union, Cash in Advance (CID), Cash Advance (CA)

Delivery Time
2-3 Week

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)
South America, Western Europe, Australia, North America, Eastern Europe, Central America, Middle East, Asia, Africa

Main Domestic Market
All India

Certifications
WHO,GMP,COA,MSDS As Per Client Requirement

About Disulfiram API

Disulfiram is a drug discovered in the 1920s used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a hangover are felt immediately after alcohol is consumed.

Specification:

Item	Specifications	Results
Appearance	white with yellowness greenish hue,to light yellow with greenish hue color crystalline powder	Positive
Assay,Titration	99.0	99.2
Color of solution	D under 440ml<0.2	0.13
Diethyldithiocarbamate	<0.015	-
Sulphate	<0.025	0.010
Chloride	<0.005	0.003
Phosphate	<0.02	0.01
Heavy metals	<0.001	-
Arsenic	<0.001	-
Impurities TLC	Total <0.5	0.3
Melting Point	69.0-72.0	70.5
Loss of Drying	<0.20	0.05
Ash content	<0.10	0.03
Solubility	Pass test	Pass test
Microbiological method	Pass test	Pass test
Identity	Pass test	Pass test
Conclusion	This product conforms toUSP28

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

High-Purity Disulfiram for Pharmaceutical Applications

With a purity of 99%, Disulfiram API is designed for reliable and efficient use in the pharmaceutical industry as a key intermediate. Manufactured and distributed across India, this powder-form ingredient ensures compliance with robust standards, serving as an effective component in the production of medications targeting alcohol dependence.

Quality Storage and Handling

Disulfiram maintains its stability and efficacy best when stored at room temperature. Its physical form as a powder requires proper handling, particularly due to its insolubility in water and high solubility in select organic solvents. Proper storage is crucial to preserve its pharmacological properties for manufacturing and supply.

FAQ's of Disulfiram API:

Q: How should Disulfiram API be stored to maintain its quality?

A: Disulfiram API should be kept at standard room temperature in a dry, well-ventilated place, away from moisture, to ensure it retains its high purity and effectiveness.

Q: What is the main pharmaceutical use of Disulfiram API?

A: The primary use of Disulfiram API is as an alcoholic deterrent. It is incorporated into medications that help treat alcohol dependence by causing unpleasant effects when alcohol is consumed.

Q: When is Disulfiram typically utilized in the pharmaceutical manufacturing process?

A: Disulfiram is used as an intermediate during the formulation of pharmaceutical products designed to deter alcohol consumption, ensuring safety and efficacy in the end medication.

Q: Where can Disulfiram API be sourced from in India?

A: Disulfiram API is supplied by various distributors, exporters, manufacturers, suppliers, traders, and wholesalers throughout India, meeting the needs of the pharmaceutical sector.

Q: What is the appearance and physical form of this Disulfiram API?

A: Disulfiram API appears as a white powder with a greenish-yellowish tint and is delivered in powder form for ease of mixing into pharmaceutical formulations.

Q: How is Disulfiram API typically dissolved or mixed during manufacturing?

A: Disulfiram is practically insoluble in water but dissolves readily in organic solvents such as acetone, chloroform, ether, and benzene, which are used in manufacturing processes.

Q: What benefits does high-purity Disulfiram offer to pharmaceutical manufacturers?

A: With its 99% purity, Disulfiram API provides reliable performance, consistent results, and ensures compliance with industry standards-benefits essential for producing effective medications.

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