Bosentan API

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Bosentan API Specification

Shelf Life
5 Years

Boiling point
218

Solubility
Poorly soluble in water (1.0 mg/100 ml)

Molecular Formula
C27H29N5O6S

Storage
Room Temperature

Medicine Name
Buclizine Hcl

Chemical Name
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide

CAS No
147536-97-8

Usage
Antihypertensive

Appearance
white crystalline powder

Physical Form
Powder

Bosentan API Trade Information

FOB Port
ALL INDIA

Payment Terms
Paypal, Western Union, Telegraphic Transfer (T/T), Cash in Advance (CID), Cash Advance (CA)

Delivery Time
2-3 Week

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)
Australia, North America, Eastern Europe, Western Europe, Middle East, Central America, South America, Asia, Africa

Main Domestic Market
All India

Certifications
WHO,GMP,COA,MSDS As Per Client Requirement

About Bosentan API

Bosentan is a mixed endothelin receptor antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR.

Specification:

Analysis Test	Specification	Result
Description	white crystalline powder	Conforms
Solubility	Easily soluble in water, unsoluble in ethanol	Conforms
PH	6.0-7.5	6.9
Solution clarity and color	solution should be clear and colorless	Conforms
Related substances	CMP 0.3% Simple impurity Total other impurity	0.01% 0.03% 0.10%
Chloride	0.05%	Conforms
Ammonium	0.05%	Conforms
Fe	0.01%	Conforms
Phosphate	0.1%	Conforms
Loss on drying	<6.0%	1.3%
Heavy metals	0.002%	Conforms
Arsenide	0.0001%	Conforms
Bacterial Endotoxins	0.3EU/mg	Conforms
Microbial Limit	Conforms	Conforms
Assay(on dried basis)	>98.0%	98.8%

Packaging details:

Packaging details:	25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage:	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat
Shelf Life:	5 years if sealed and store away from direct sun light.

High-Quality Manufacturing

Our Bosentan API is manufactured under strict quality controls, ensuring reliability and pharmaceutical-grade purity. Every batch undergoes rigorous testing to meet the standards required by the global pharmaceutical industry. As Indian exporters, we support bulk orders and provide timely deliveries worldwide.

Applications in Hypertension Management

Bosentan API plays a significant role in the formulation of antihypertensive medicines. It acts as a dual endothelin receptor antagonist, helping to manage and treat high blood pressure and associated cardiovascular conditions effectively. The API's chemical stability ensures consistent efficacy in medicinal preparations.

FAQ's of Bosentan API:

Q: How should Bosentan API be stored to maintain its shelf life?

A: Bosentan API should be stored at room temperature, away from excessive moisture and direct sunlight. Proper storage helps maintain its quality and ensures a shelf life of up to 5 years.

Q: What is the recommended usage of Bosentan API?

A: Bosentan API is primarily intended for pharmaceutical manufacturing, especially in the production of antihypertensive medications. It must be processed by qualified professionals in authorized facilities.

Q: When is Bosentan API typically utilized in pharmaceutical production?

A: Manufacturers employ Bosentan API during the synthesis of formulations targeting hypertension and related cardiovascular disorders. It is incorporated at the initial stages of drug development for optimal results.

Q: Where does your company distribute Bosentan API?

A: We distribute Bosentan API throughout India and also export to international clients, serving as a manufacturer, supplier, exporter, and wholesaler for pharmaceutical organisations worldwide.

Q: What are the benefits of choosing Bosentan API from your company?

A: Clients benefit from our commitment to quality, reliable global supply, and competitive pricing. Our Bosentan API adheres to stringent manufacturing requirements, ensuring consistent performance and regulatory compliance.

Q: How is Bosentan API processed for medical applications?

A: This API is typically formulated with other pharmaceutical ingredients under controlled manufacturing settings. The process ensures dosage accuracy and product safety for medical use.

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