Amilorideis apotassium-sparing diuretic,used in the management ofhypertensionandcongestive heart failure. Amiloride was also tested as treatment ofcystic fibrosis.
Mechanism of Action:
Amiloride works by directly blocking theepithelial sodium channel(ENaC) thereby inhibitingsodiumreabsorption in the latedistal convoluted tubules, connecting tubules, and collecting ducts in thekidneys(this mechanism is the same fortriamterene).This promotes the loss of sodium and water from the body, but without depletingpotassium. The drug is often used in conjunction withthiazide(e.g.co-amilozide) orloop diuretics(e.g.co-amilofruse). Due to its potassium-sparing capacities,hyperkalemia(high blood potassium levels) is occasionally observed in patients taking amiloride. The risk is high in concurrent use ofACE inhibitorsorspironolactone.
Packaging details:
| Packaging details: | 25KG/Drum with double plastic bag inside; Aluminium foil bag with plastic bag inside and carton box outside for small quantity |
| Storage: | Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
| Shelf Life: | 5 years if sealed and store away from direct sun light. |

Price:
Price 20.0 USD ($) / Kilograms
Minimum Order Quantity : 10 Kilograms
Appearance : White to offwhite powder
Molecular Formula : C16H18ClNO6S2
Physical Form : Powder
Storage : Dry Place
Price 35.0 USD ($) / Kilograms
Minimum Order Quantity : 1 Kilograms
Appearance : White crystalline powder
Molecular Formula : C14H22N2O3
Physical Form : Powder
Storage : Keep away from moisture
Price 20.0 USD ($) / Kilograms
Minimum Order Quantity : 10 Kilograms
Appearance : white crystalline powder
Molecular Formula : C8H8KNO5
Physical Form : Powder
Storage : Keep away from moisture
Price 28.0 USD ($) / Kilograms
Minimum Order Quantity : 1 Kilograms
Appearance : White crystalline powder.
Molecular Formula : C15H22O5 (282.4)
Physical Form : Powder
Storage : Keep away from moisture